If you pick up from the following alphabet, the sixth and the fourteenth letters from your right and then pick up the fifth and twentieth letters from your left and from a meaningful word, what is the first letter of that word ?
A  B  C  D  E  F  G  H  I  J  K  L  M
N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Answer: A. M

The sixth and fourteenth letters from the right are U and M respectively. The fifth and twentieth letters from the left are E and T respectively. Clearly, the word formed is MUTE.
So, the first letter is M.