One couple is QP.
Now, R and U are the children of T. So, the other couple is TS.
T is a teacher.
S is a female doctor.
Q is a lawyer.
Clearly, P is a housewife and hence a female.
S is the mother of R and U.
P has one son and on grandson.
Clearly, T is the son of P and R or U is the grandson.
The grandson is a male engineer and the grand-daughter is a student.
Hence, P is the grandmother of R.