Q, the Doctor, is the father of T. S, the Housewife, is the grandmother of T and hence the mother of Q. Since there are only two married couples one being that of Q, the grandfather of R i.e., U must be married to S. Thus, R and T will be both children of Q and these must be the students. So, P, who remains, shall be the wife of Q and she alone can be the nurse. Thus, U must be the contractor.

Clearly, R and T are children of same parents. So, R will be the sister of T.